See what standard medicine misses.

Aven Clarity decodes the root causes — the toxins, the exposome, the biological connections — that standard care was never designed to find.

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HEALTH ASSISTANT

Welcome, Sarah. Before we get into anything, I want to know a few things about how you live — because about 70% of toxin exposure comes from food, especially leafy greens grown in older soils. Five quick questions.

1. How often do you eat leafy greens (kale, spinach, chard)?

HEALTH ASSISTANT

Thank you. That's enough for me to give you a first picture — before any labs.

Based on what you've told me — your home age, your ZIP code's water and soil reports, and your diet — the engine flagged something worth a closer look.

Look at the right panel ↗

HEALTH ASSISTANT

This is a hypothesis, not a diagnosis. But it's the most informative thing I can tell you in 60 seconds. Want to confirm or rule it out?

HEALTH ASSISTANT

Before we go deeper — is there anything specific going on for you health-wise? A symptom, a concern, anything you've been wrestling with?

I've had chronic fatigue for over a year. I've seen 3 doctors. They ran labs, said I'm "basically healthy," and offered me HRT. I refused. I bought a Function Health subscription out of desperation. The 100+ markers were comprehensive and meaningless. I have no idea what to do.

HEALTH ASSISTANT
Insight
Chronic fatigue with normal standard labs is one of the hardest problems in medicine. Most workups look for disease — they're not built to find upstream contributors like environmental exposures. It's not surprising you're stuck. Let me look in a different place.
Opportunity
Since you already have the Function Health report, drop it in. I'll match every marker against the engine's 14,000-node model and see what your existing data was trying to tell you. You don't need to redo work you've already paid for.
HEALTH ASSISTANT

Pick what you have. PDF, image, or genomic export — I can read all of them.

HEALTH ASSISTANT

Reading Sarah_FunctionHealth_Report.pdf now…

GPT-4.1 vision is extracting markers, the test taxonomy is matching them to the engine's input IDs.

HEALTH ASSISTANT

Done. The engine has ingested your 98 markers and re-evaluated.

And — Sarah, look at the panel on the right. The hypothesis I had on you in 60 seconds, before any labs, just got confirmed and sharpened by your Function Health data.

Heavy Metal Exposure: 64% → 92%

HEALTH ASSISTANT

Function Health had every one of these markers in the report you already paid for. They didn't connect them to a story.

I just did — by combining your data with your ZIP code and a 14,000-node clinical model that took Dr. Joe Pizzorno 20 years to build.

Want me to show you exactly how I got there?

THE SYMPTOM-CAUSE BRIDGE

Here's why your fatigue isn't a mystery anymore.

Your symptom, the metabolic pathway, and your data — connected by the engine's reasoning.

Symptom to Cause Bridge for Sarah's chronic fatigue A diagram linking chronic fatigue to its biochemical pathway (lead inhibition of ALAD, reduced heme synthesis, mitochondrial dysfunction) and the supporting data points from Sarah's Function Health report and her ZIP code. YOUR SYMPTOM THE PATHWAY YOUR DATA Chronic Fatigue your primary concern ~12 months Lead inhibits ALAD enzyme; blocks heme synthesis Reduced heme production → functional iron deficiency Impaired O₂ + energy transport cells starved of fuel Compensatory depletion zinc + ceruloplasmin drop Zinc — low 62 µg/dL · Function Health Ceruloplasmin — low 18 mg/dL · Function Health ALT — elevated 42 U/L · Function Health Alkaline phosphatase — low 38 U/L · Function Health ZIP 48202 + 1932 home elevated lead exposure prior

Lead competitively inhibits ALAD, an enzyme essential to heme synthesis. Reduced heme means functional iron deficiency — your body can't efficiently carry oxygen or produce cellular energy, even if your iron labs look "normal." That's the chronic fatigue you've been experiencing for the past year.

Your low zinc and low ceruloplasmin are textbook signs of chronic low-level lead exposure: your body has been depleting both to compensate. Combined with your 1932 Detroit home and elevated ALT, the engine ranks heavy metal toxicity as your single most likely upstream cause.

This is the engine's highest-probability hypothesis given your data. It's not a diagnosis. It's a hypothesis precise enough to take to a doctor and confirm.

YOU'VE SEEN WHAT THE ENGINE FOUND

Now let's turn the hypothesis into a plan.

Everything up to this point — the Bridge, the engine's reasoning — is free. The next part is the actionable protocol.

STAGE 6 · TEST — CONFIRM THE HYPOTHESIS

Here's exactly what to ask your doctor for.

The engine identifies the tests that would most reduce uncertainty about heavy metal toxicity — and gives you the billing codes so insurance pays.

💡 Insurance-billable · CPT codes included
Test Sample CPT code
Blood Lead Level (BLL)
Direct measure of recent lead exposure — primary confirmation
 Blood draw 83655
Urine heavy metals panel
Measures excreted heavy metals — complements blood lead for full picture
 Urine 83018
RBC zinc
Confirms the low zinc finding from your Function Health report
 Blood draw 84630

A doctor-ready summary for the BLL test:

Request: Blood Lead Level (CPT 83655)

Prepared by Aven Clarity · For: Sarah Chen · Date: Apr 9, 2026

Why this test: Patient is 42 yo female, lives in a 1932 home in Detroit (ZIP 48202) — an EPA-flagged water district for lead. Unfiltered municipal water, reports farmed fish consumption and garden produce in older soil. 12-month history of chronic fatigue with three prior WNL workups.

Environmental risk factors are the primary basis for this request.

"I live in a 1932 home in Detroit's 48202 zip code, which has documented lead concerns in the water supply. I'd like to rule out chronic low-level lead exposure as a contributor to my fatigue. Please order a Blood Lead Level (CPT 83655)."

Supplementary context: A probabilistic health assessment also identified lab patterns (low zinc, low ceruloplasmin, elevated ALT, low alkaline phosphatase) that are consistent with the environmental picture above. These are provided as additional context — the environmental factors are the primary clinical basis.

STAGE 7 · TREAT — YOUR PROTOCOL

Specific actions, not generic advice.

Categorized so you know what to do yourself, what to discuss with your doctor, and what to bring to a specialist.

Dietary
  • Eliminate farm-raised fishHighest dietary lead source for your demographic. Switch to wild-caught Alaskan salmon, sardines.
  • Increase cruciferous vegetables 4x/weekSulforaphane supports your detox pathways. Broccoli sprouts are highest yield.
  • Test your garden soil for lead before eating from itDetroit topsoil contamination is well-documented. If your garden is organic and soil tests clean, continue — organic home-grown is ideal. The risk is primarily from non-organic retail produce grown in contaminated soil.
Supplements (OTC)
  • Liposomal glutathione, 500mg/dayQuicksilver Scientific or Pure Encapsulations · ~$45/mo
  • Zinc picolinate, 30mg/day with foodReplenishes the depletion seen in your Function Health zinc · Thorne · ~$15/mo
  • Vitamin C, 1000mg/dayCofactor for chelation pathways · any reputable brand
Bring to your doctor MD only
  • Order a Blood Lead Level (CPT 83655)Use the doctor-ready summary on the previous screen.
  • Discuss DMSA chelation protocolOnly if BLL confirms exposure. Physician-supervised only.
  • Find an environmental medicine specialist3 in your area — see referrals tab.
Lifestyle & home
  • AquaTru countertop RO filterRemoves lead, arsenic, fluoride. ~$450, no installation. Better than whole-house for your zip's contaminant profile.
  • Home dust lead test kit$15 mail-in kit. Confirm whether your 1932 home has active lead dust.
  • Infrared sauna 3x/weekMobilizes stored heavy metals via sweat. Public sauna fine if home unit isn't an option.
STAGE 7.5 · DOCTOR HANDOFF

One page. Your doctor gets the whole story.

Print it, email it, or hand it to your next appointment. Cites engine reasoning with specific markers and asks.

SHARE

Send to your doctor

What's in the PDF Patient context, the relevant Function Health markers, the specific ask with CPT code, the engine's reasoning, and a citation to Dr. Pizzorno's reference work. Designed to take a clinician 60 seconds to read.
STAGE 8 · ONGOING SUPPORT

This isn't a one-shot report. We're here as your data grows.

Every new lab, every check-in, every follow-up — the engine re-evaluates. Your protocol evolves with you.

Community — people on the same path

Connect with others who match your exposure profile and see what's working for them.

127 people in the Aven Clarity community match your profile within 80%. 73% reported improved energy after following a similar protocol over 8–12 weeks.

Connected apps

Scan products at the store. Your exposure profile gets smarter every time.

Yuka
Clearya
More

Adherence & progress tracking

Daily check-ins on your protocol. Visualize your energy improvement against your follow-up testing schedule.

Next milestone: BLL recheck in 8 weeks · RBC zinc in 12 weeks

Add your family

If your home is contaminated, your family is exposed too. Add a profile for your spouse and kids — same engine, separate health stories.

Children under 6 have 5x higher lead absorption rates than adults. Worth checking.

Other health stories the engine can tell

Once we have your data, we can help you explore brain health, longevity, fertility, and more — same engine, new questions.

Brain
Longevity
Fertility

Re-evaluation, forever

Upload your next labs. The engine re-runs, your protocol updates, your story moves forward. This is the loop.

Sarah's next check-in: in 7 days

"Agency is the ultimate medicine. We don't replace your care team — we give you the intelligence to lead them."

— end of Sarah's journey